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Berl Munch
Tierarztl Wochenschr 1999 Oct-Nov;112(10-11):400-6
Efficacy and tolerance
of a calcium-magnesium-aspartate solution in the treatment of
hypocalcemic parturient paresis in cows
[Article in
German]
Andresen U,
Kietzmann M, Andresen P.
Institut fur
Pharmakologie, Toxikologie und Pharmazie, Tierarztlichen Hochschule
Hannover.
The systemic
tolerance of a solution of calcium aspartate and magnesium aspartate was
studied in 7 cows.
Intravenously
administered dosages of 500 ml per cow were well tolerated. A twofold
increase of the serum calcium concentration was measured. In 2 cows
which were treated with 1000 ml of the solution a threefold increased
calcium concentration and heart arrhythmia were found.
The clinical
efficacy of the solution was demonstrated in a study with 44
hypocalcemic cows. A long lasting increase of the serum calcium as well
as an enhanced phosphorus concentration were measurable.
In conclusion,
the calcium-magnesium-aspartate solution seems to be an efficacious and
well tolerated alternative for the treatment of hypocalcemia in cows.
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