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In this issue:

1. Share Success: Letters From Readers
2. Research News: Excercise May Help Prevent Parkinson’s Disease
3. Useful Links
4. What Are Others Saying About EZorb and Marvlix?

Letter I: From Ellen S.K.
Received at Testimonial Submit Form Tuesday, May 30, 2023 at 02:08 PM PDT
(Unedited)

I just found out that I have to deal with Fibromyalgia but I didn't wont to take the strong medication which you will get from your doctor. So I ordered on April 09, 2023 one bottle of EZorb.

After 4 weeks taking the EZorb I feel already better, best of all I started to sleep again.

I don't feel that much pain at night anymore. On your Dosage/Weight table you give a Startup Daily for the first 3 months. I talked to my doctor and he told me to try EZorb for 3 months to see how much better I will feel after this time. So far so good.

I also have High cholesterol. Taking medication with statins gave me much trouble, I had to stop taking them. Tried even different medication without statins but they gave me trouble too. Now I would like to try your Marvlix but I don't know how much capsules I have to take per day. This would be then the only medication for me to take for my high cholesterol.

I also would like to take it for 3 month to see the results how they would affect on me. My doctor would like having me to take a blood test after this time.

Ellen S.K.

Letter II: From Susan C.
Received at Share Success Saturday, May 20, 2023 at 08:56 AM PDT
(Unedited)

Hi there!

I just wanted to mention that on my 5th day of taking Ezorb power 3x’s per day, the plaque on my lower bottom teeth went away.

I had been planning on using a pick a couple of nights before and in the process, got sidetracked with something else. On my way to work a couple of days later, I noticed the plaque was not there anymore. I had space between my bottom front teeth.

Is this just coincidence? Is it too fast for Ezorb to work like that? I can’t help but think that since I’m drinking it, I’m sure it coats the teeth .

Susan C.

Our newsletter reaches over 230,000 subscribers worldwide. Success stories you shared in the past have made a great impact on many people's life.

Please email your story to sharesuccess@ezorbonline.com or simply post it to Testimonial Submit Form. Your personal information will never be revealed to the public.

Physical frailty may be a risk factor for Parkinson’s disease, particularly in people with a high genetic risk for the condition, suggest study findings published in JAMA Neurology.

“Integrating frailty assessment into the primary prevention of Parkinson’s disease may favor the identification of high-risk individuals”, say the study researchers, led by Liangkai Chen, from Huazhong University of Science and Technology in Wuhan, China.

They assessed 314,998 middle-aged and older adults living in the UK over a mean 12.3-year follow-up, 1916 of whom developed new-onset Parkinson’s disease. The risk for Parkinson’s disease increased 26% among the 135,885 (43.1%) individuals diagnosed with prefrailty who met up to two of the five criteria for the Fried frailty phenotype of weight loss, exhaustion, low physical activity, slow walking speed and low grip strength, and by 87% among those diagnosed with frailty who met three or more phenotype criteria.

“We adopted the frailty phenotype to assess physical frailty instead of the frailty index or frailty scale, which is more clinically practical and the most frequently used epidemiological measure”, the investigators explain.

They add that all the phenotype criteria were significantly associated with incident Parkinson’s disease, except for weight loss, and there was a positive association between the risk for Parkinson’s disease and the accumulation of frailty components, with the risk increasing by 21% with each additional component.

People with prefrailty or frailty were more likely than those without to be older, female, more deprived, current smokers and have higher BMI and more long-term morbidities.

And the researchers report that an increased risk of incident Parkinson’s disease was associated with worse frailty and an increased genetic risk on the polygenic risk score (PRS). Indeed, participants with frailty who were in the highest tertile of PRS had the greatest risk of Parkinson’s disease, at a hazard ratio of 3.22, compared with nonfrail individuals in the lowest tertile of PRS. By contrast, among nonfrail individuals, the risk of Parkinson’s disease decreased by 43%, 42% and 55% among those in the lowest, intermediate and top tertiles of PRS, respectively.

“Our results suggest that improvement of physical frailty would benefit individuals even with a high genetic risk of Parkinson’s disease”, they say.

The authors note that the association between prefrailty and frailty was “robust” after taking into account sociodemographic factors, lifestyles, multiple morbidities and genetic background, with an absolute difference in the rate for Parkinson’s disease of 1.6 per 100,000 person-years among people with prefrailty and 5.1 for those with frailty compared with nonfrail individuals.

“Our findings support that frailty might be a valuable tool in Parkinson’s disease screening”, the researchers comment.

“In addition, when patients present with prefrailty or frailty strategies to change patients’ lifestyles could be tailored to prevent or delay the development of Parkinson’s disease.”

Original research was published in JAMA Neurol 2023; doi:10.1001/jamaneurol.2023.01.

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