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Berl Munch Tierarztl Wochenschr 1999 Oct-Nov;112(10-11):400-6


Efficacy and tolerance of a calcium-magnesium-aspartate solution in the treatment of hypocalcemic parturient paresis in cows


[Article in German]


Andresen U, Kietzmann M, Andresen P.


Institut fur Pharmakologie, Toxikologie und Pharmazie, Tierarztlichen Hochschule Hannover.


The systemic tolerance of a solution of calcium aspartate and magnesium aspartate was studied in 7 cows.


Intravenously administered dosages of 500 ml per cow were well tolerated. A twofold increase of the serum calcium concentration was measured. In 2 cows which were treated with 1000 ml of the solution a threefold increased calcium concentration and heart arrhythmia were found.


The clinical efficacy of the solution was demonstrated in a study with 44 hypocalcemic cows. A long lasting increase of the serum calcium as well as an enhanced phosphorus concentration were measurable.


In conclusion, the calcium-magnesium-aspartate solution seems to be an efficacious and well tolerated alternative for the treatment of hypocalcemia in cows.




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