Makers of EZorb and Marvlix
 

EZorb®

 
 

Mutat Res 1998 Jun 5;401(1-2):111-20

 

Radioprotective effect of zinc aspartate on mouse spermatogenesis: a flow cytometric evaluation.

 

Krishnamurthy H, Jagetia GC, Jyothi P.

Department of Radiobiology, Kasturba Medical College, Manipal 576 119, India.

 

The radioprotective effect of zinc aspartate on spermatogonial cells of whole-body irradiated mice was studied using flow cytometry.

 

Adult male Swiss albino mice were treated with 30 mg/kg body weight of zinc aspartate 30 min before exposure to 0, 0.5, 1, 2 and 3 Gy of gamma-radiation. The animals were killed 7 to 70 days postirradiation and the relative percentages of different germ cells were analyzed by flow cytometry.

 

A significant increase (p<0.002, 0. 0001, 0.005 and 0.008 for 0.5, 1, 2 and 3 Gy, respectively) in the relative percentage of spermatogonial (2C) population was observed in mice treated with zinc aspartate before exposure to different doses of gamma-radiation, compared to the irradiated controls on day 35 posttreatment.

Also mean of each radiation dose of all the intervals studied showed a significant (p<0.03) increase in the relative percentage of spermatogonia. Despite the increase in the relative percentage of spermatogonia, the relative percentage of tetraploid cells (4C) remained higher in the zinc aspartate treated mice, compared to the irradiated controls.

 

However, there was no change in the haploid populations viz. round (1C) and elongated (HC) spermatids of the zinc aspartate pretreated animals compared to irradiated controls.

 

These data suggests that zinc aspartate pretreatment protects spermatogonia and

tetraploid cells from radiation-induced cell killing.

 

 

 

Osteoporosis - Comparison of Treatment Options

Compare EZorb Calcium with Osteoporosis Prescription Drugs

Bone and Joint Overview

Clinical Studies

The Importance of Collagen for Bone and Joint Health

Causes of Osteoarthritis

Treatment of Osteoarthritis - Review of Various Options

Is Rheumatoid Arthritis (RA) Really an Autoimmune Disease?

Breaking the Vicious Circle of Fibromyalgia

Bone Spur - A Natural Approach

Do You Suffer from Heel Spurs?

Juvenile Rheumatoid Arthritis

Quick EZorb Calcium Osteoporosis Facts

 

Ready to order? Go directly to our online store, or call 1-800-395-5715. Open 24 hours a day, 7 days a week. You may also use the mail order form to mail us your order.

 

 

 

 

Copyright © 2020 Elixir Industry. All Rights Reserved.